STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGPL1Sphingosine-1-phosphate lyase 1. (568 aa)    
Predicted Functional Partners:
SGPP1
Sphingosine-1-phosphate phosphatase 1.
    
 0.988
SPHK2
Sphingosine kinase 2.
   
 0.979
SGPP2
Sphingosine-1-phosphate phosphatase 2.
    
 0.978
SPHK1
Sphingosine kinase 1.
 
 
 0.974
PLPP1
Phospholipid phosphatase 1.
    
 0.932
PLPP3
acidPPc domain-containing protein.
    
 0.921
SPNS2
Sphingolipid transporter 2.
      
 0.869
CERK
Ceramide kinase.
   
 0.660
ABAT
4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.656
METTL7B
Methyltransferase like 7B.
   
  
 0.609
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.