node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABRAXAS1 | BABAM1 | ENSOARP00000003059 | ENSOARP00000018675 | Abraxas 1, BRCA1 A complex subunit. | BRISC and BRCA1 A complex member 1. | 0.999 |
ABRAXAS1 | BABAM2 | ENSOARP00000003059 | ENSOARP00000020899 | Abraxas 1, BRCA1 A complex subunit. | BRISC and BRCA1 A complex member 2. | 0.998 |
ABRAXAS1 | BARD1 | ENSOARP00000003059 | ENSOARP00000020704 | Abraxas 1, BRCA1 A complex subunit. | BRCA1 associated RING domain 1. | 0.995 |
ABRAXAS1 | BRCA1 | ENSOARP00000003059 | ENSOARP00000005185 | Abraxas 1, BRCA1 A complex subunit. | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | 0.999 |
ABRAXAS1 | BRCC3 | ENSOARP00000003059 | ENSOARP00000003804 | Abraxas 1, BRCA1 A complex subunit. | BRCA1/BRCA2-containing complex subunit 3. | 0.999 |
ABRAXAS1 | UBC | ENSOARP00000003059 | ENSOARP00000019508 | Abraxas 1, BRCA1 A complex subunit. | Ubiquitin-related; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repa [...] | 0.561 |
ABRAXAS1 | W5P8Y3_SHEEP | ENSOARP00000003059 | ENSOARP00000006890 | Abraxas 1, BRCA1 A complex subunit. | Uncharacterized protein. | 0.658 |
BABAM1 | ABRAXAS1 | ENSOARP00000018675 | ENSOARP00000003059 | BRISC and BRCA1 A complex member 1. | Abraxas 1, BRCA1 A complex subunit. | 0.999 |
BABAM1 | BABAM2 | ENSOARP00000018675 | ENSOARP00000020899 | BRISC and BRCA1 A complex member 1. | BRISC and BRCA1 A complex member 2. | 0.999 |
BABAM1 | BARD1 | ENSOARP00000018675 | ENSOARP00000020704 | BRISC and BRCA1 A complex member 1. | BRCA1 associated RING domain 1. | 0.939 |
BABAM1 | BRCA1 | ENSOARP00000018675 | ENSOARP00000005185 | BRISC and BRCA1 A complex member 1. | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | 0.992 |
BABAM1 | BRCC3 | ENSOARP00000018675 | ENSOARP00000003804 | BRISC and BRCA1 A complex member 1. | BRCA1/BRCA2-containing complex subunit 3. | 0.999 |
BABAM1 | UBC | ENSOARP00000018675 | ENSOARP00000019508 | BRISC and BRCA1 A complex member 1. | Ubiquitin-related; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repa [...] | 0.538 |
BABAM1 | W5P8Y3_SHEEP | ENSOARP00000018675 | ENSOARP00000006890 | BRISC and BRCA1 A complex member 1. | Uncharacterized protein. | 0.663 |
BABAM2 | ABRAXAS1 | ENSOARP00000020899 | ENSOARP00000003059 | BRISC and BRCA1 A complex member 2. | Abraxas 1, BRCA1 A complex subunit. | 0.998 |
BABAM2 | BABAM1 | ENSOARP00000020899 | ENSOARP00000018675 | BRISC and BRCA1 A complex member 2. | BRISC and BRCA1 A complex member 1. | 0.999 |
BABAM2 | BARD1 | ENSOARP00000020899 | ENSOARP00000020704 | BRISC and BRCA1 A complex member 2. | BRCA1 associated RING domain 1. | 0.844 |
BABAM2 | BRCA1 | ENSOARP00000020899 | ENSOARP00000005185 | BRISC and BRCA1 A complex member 2. | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | 0.886 |
BABAM2 | BRCC3 | ENSOARP00000020899 | ENSOARP00000003804 | BRISC and BRCA1 A complex member 2. | BRCA1/BRCA2-containing complex subunit 3. | 0.999 |
BABAM2 | UBC | ENSOARP00000020899 | ENSOARP00000019508 | BRISC and BRCA1 A complex member 2. | Ubiquitin-related; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repa [...] | 0.562 |