STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FRMD4AFERM domain containing 4A. (888 aa)    
Predicted Functional Partners:
STK35
Serine/threonine kinase 35; Belongs to the protein kinase superfamily.
      
 0.806
ABHD15
Abhydrolase domain containing 15.
   
  
 0.765
TMEM150A
Transmembrane protein 150A.
      
 0.755
HSPH1
Heat shock protein family H (Hsp110) member 1.
   
  
 0.711
PLXDC2
Plexin domain containing 2.
      
 0.700
RNF144B
RBR-type E3 ubiquitin transferase.
      
 0.695
CYTH3
Cytohesin 3.
    
 
 0.684
CYTH4
Cytohesin 4.
    
 
 0.684
CYTH1
Cytohesin 1.
    
 
 0.662
CYTH2
Uncharacterized protein.
    
 
 0.662
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.