STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PARP3PARP alpha-helical domain-containing protein. (260 aa)    
Predicted Functional Partners:
W5P9H5_SHEEP
Poly [ADP-ribose] polymerase.
 
     0.949
CASP7
Caspase 7; Belongs to the peptidase C14A family.
    
 0.936
APLF
Aprataxin and PNKP like factor.
    
 
 0.928
CASP3
Caspase 3; Belongs to the peptidase C14A family.
    
 0.918
CASP9
Caspase 9; Belongs to the peptidase C14A family.
    
 0.918
W5NUY5_SHEEP
Peptidase S1 domain-containing protein.
   
 
  0.903
W5NYD4_SHEEP
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
 
  0.903
MCP-3
Mast cell protease 3.
   
 
  0.903
W5P415_SHEEP
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
   
 
  0.903
ZBTB24
Zinc finger and BTB domain containing 24.
    
 
 0.873
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.