node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFTUD2 | PHF5A | ENSOARP00000009748 | ENSOARP00000019582 | Elongation factor Tu GTP binding domain containing 2. | PHD finger protein 5A. | 0.891 |
EFTUD2 | SNRNP70 | ENSOARP00000009748 | ENSOARP00000013507 | Elongation factor Tu GTP binding domain containing 2. | Small nuclear ribonucleoprotein U1 subunit 70. | 0.735 |
EFTUD2 | SNRPA | ENSOARP00000009748 | ENSOARP00000007457 | Elongation factor Tu GTP binding domain containing 2. | SNPRA. | 0.941 |
EFTUD2 | SNRPA1 | ENSOARP00000009748 | ENSOARP00000017939 | Elongation factor Tu GTP binding domain containing 2. | LRRcap domain-containing protein. | 0.979 |
EFTUD2 | SNRPC | ENSOARP00000009748 | ENSOARP00000011602 | Elongation factor Tu GTP binding domain containing 2. | U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] | 0.778 |
EFTUD2 | SNRPD1 | ENSOARP00000009748 | ENSOARP00000003638 | Elongation factor Tu GTP binding domain containing 2. | Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. | 0.987 |
EFTUD2 | SNRPD2-2 | ENSOARP00000009748 | ENSOARP00000017976 | Elongation factor Tu GTP binding domain containing 2. | Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. | 0.955 |
EFTUD2 | SNRPD3 | ENSOARP00000009748 | ENSOARP00000015006 | Elongation factor Tu GTP binding domain containing 2. | Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. | 0.990 |
EFTUD2 | SNRPF | ENSOARP00000009748 | ENSOARP00000012706 | Elongation factor Tu GTP binding domain containing 2. | Small nuclear ribonucleoprotein polypeptide F. | 0.992 |
EFTUD2 | W5P851_SHEEP | ENSOARP00000009748 | ENSOARP00000006606 | Elongation factor Tu GTP binding domain containing 2. | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. | 0.995 |
PHF5A | EFTUD2 | ENSOARP00000019582 | ENSOARP00000009748 | PHD finger protein 5A. | Elongation factor Tu GTP binding domain containing 2. | 0.891 |
PHF5A | SNRNP70 | ENSOARP00000019582 | ENSOARP00000013507 | PHD finger protein 5A. | Small nuclear ribonucleoprotein U1 subunit 70. | 0.787 |
PHF5A | SNRPA | ENSOARP00000019582 | ENSOARP00000007457 | PHD finger protein 5A. | SNPRA. | 0.951 |
PHF5A | SNRPA1 | ENSOARP00000019582 | ENSOARP00000017939 | PHD finger protein 5A. | LRRcap domain-containing protein. | 0.995 |
PHF5A | SNRPC | ENSOARP00000019582 | ENSOARP00000011602 | PHD finger protein 5A. | U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] | 0.861 |
PHF5A | SNRPD1 | ENSOARP00000019582 | ENSOARP00000003638 | PHD finger protein 5A. | Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. | 0.946 |
PHF5A | SNRPD2-2 | ENSOARP00000019582 | ENSOARP00000017976 | PHD finger protein 5A. | Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. | 0.931 |
PHF5A | SNRPD3 | ENSOARP00000019582 | ENSOARP00000015006 | PHD finger protein 5A. | Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. | 0.964 |
PHF5A | SNRPF | ENSOARP00000019582 | ENSOARP00000012706 | PHD finger protein 5A. | Small nuclear ribonucleoprotein polypeptide F. | 0.986 |
PHF5A | W5P851_SHEEP | ENSOARP00000019582 | ENSOARP00000006606 | PHD finger protein 5A. | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. | 0.990 |