STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARL6IP4ADP ribosylation factor like GTPase 6 interacting protein 4. (313 aa)    
Predicted Functional Partners:
THRAP3
Thyroid hormone receptor associated protein 3.
    
 
 0.774
SUB1
SUB1 regulator of transcription.
      
 0.693
FBRS
Fibrosin.
      
 0.538
GPC1
Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
      
 0.538
NUDT21
Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]
      
 0.520
RBM39
RNA binding motif protein 39.
   
 
 0.511
LSM6
Sm domain-containing protein.
      
 0.483
PIP4K2B
Phosphatidylinositol-5-phosphate 4-kinase type 2 beta.
    
   0.483
W5PPU9_SHEEP
Sm domain-containing protein.
      
 0.483
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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