STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIRPAUncharacterized protein. (506 aa)    
Predicted Functional Partners:
CD47
CD47 molecule.
   
 0.983
TYROBP
TYRO protein tyrosine kinase binding protein.
   
 0.926
TREM2
Triggering receptor expressed on myeloid cells 2.
   
 0.920
SYK
Tyrosine-protein kinase.
   
 0.919
FCGR3A
Uncharacterized protein.
   
 0.740
W5P9S7_SHEEP
Uncharacterized protein.
    
 0.695
PTPN11
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
    
 0.695
CD79A
CD79a molecule.
   
 0.613
CD163
CD163 molecule.
   
  
 0.587
CD79B
CD79b molecule.
   
 0.585
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.