STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VPS37BVPS37B subunit of ESCRT-I. (246 aa)    
Predicted Functional Partners:
TSG101
Tumor susceptibility 101.
   
 0.991
VPS28
VPS28 subunit of ESCRT-I; Belongs to the VPS28 family.
   
 0.991
MVB12A
Multivesicular body subunit 12A.
   
 0.971
MVB12B
Multivesicular body subunit 12B.
   
 0.968
LOC101107266
Uncharacterized protein.
     
 0.848
UBAP1
Ubiquitin associated protein 1.
    
 0.843
VPS36
Vacuolar protein sorting 36 homolog.
     
 0.834
SNF8
Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.
     
 0.828
CHMP2A
Charged multivesicular body protein 2A.
    
 0.823
CHMP7
Charged multivesicular body protein 7.
     
 0.782
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.