STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5PCB0_SHEEPPR domain zinc finger protein 12; Involved in the positive regulation of histone H3-K9 dimethylation; Belongs to the class V-like SAM-binding methyltransferase superfamily. (367 aa)    
Predicted Functional Partners:
GPR101
G protein-coupled receptor 101; Belongs to the G-protein coupled receptor 1 family.
      
 0.689
SCN11A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
      
 0.512
DRGX
Dorsal root ganglia homeobox.
    
 
 0.485
OR6F1
Olfactory receptor.
      
 0.485
MARCHF1
RING-CH-type domain-containing protein.
   
  
 0.484
NPY5R
Neuropeptide Y receptor Y5.
      
 0.483
PHOX2B
Uncharacterized protein.
      
 0.483
W5NS90_SHEEP
Uncharacterized protein.
      
 0.482
PMFBP1
Uncharacterized protein.
      
 0.482
GPR161
G protein-coupled receptor 161; Belongs to the G-protein coupled receptor 1 family.
      
 0.481
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.