STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
S1PR3Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (383 aa)    
Predicted Functional Partners:
GNAI2
Uncharacterized protein.
    
 0.955
GNAI1
G protein subunit alpha i1.
    
 0.955
GNAI3
G protein subunit alpha i3.
    
 0.955
GNA12
G protein subunit alpha 12.
    
 0.951
GNA13
G protein subunit alpha 13.
    
 0.950
S1PR2
Sphingosine-1-phosphate receptor 2; Belongs to the G-protein coupled receptor 1 family.
     
0.947
S1PR1
Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family.
  
 
0.943
GNAQ
G protein subunit alpha q.
    
 0.931
HBEGF
Heparin binding EGF like growth factor.
     
 0.747
SPHK1
Sphingosine kinase 1.
      
 0.694
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.