STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARL8BUncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (176 aa)    
Predicted Functional Partners:
LAMTOR2
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2.
    
 0.876
FYCO1
FYVE and coiled-coil domain containing 1.
    
 0.871
ITSN2
Intersectin 2.
    
 0.833
ZFYVE27
Zinc finger FYVE-type containing 27.
    
 
 0.771
ITSN1
Intersectin 1.
    
 0.742
LAMTOR3
Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3.
   
 0.709
PLEKHM1
Pleckstrin homology and RUN domain containing M1.
    
 
 0.693
VPS11
Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.
    
 
 0.689
CHCHD1
Coiled-coil-helix-coiled-coil-helix domain containing 1.
   
  
 0.678
SLC38A9
Solute carrier family 38 member 9.
     
 0.660
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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