KPNB1 protein (Ovis aries) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

KPNB1

Karyopherin subunit beta 1. (866 aa)

Predicted Functional Partners:

KPNA1

0.991

RAN

0.989

SNUPN

0.982

RANBP2

0.973

KPNA6

0.960

SREBF2

0.944

DKC1

0.940

KPNA5

0.940

KPNA3

0.939

EXOSC10

0.937

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DKC1	KPNB1	ENSOARP00000003242	ENSOARP00000009086	PUA domain-containing protein.	Karyopherin subunit beta 1.	0.940
EXOSC10	KPNA1	ENSOARP00000003920	ENSOARP00000021625	Exosome component 10.	Importin subunit alpha; Functions in nuclear protein import.	0.560
EXOSC10	KPNA3	ENSOARP00000003920	ENSOARP00000009249	Exosome component 10.	Importin subunit alpha; Functions in nuclear protein import.	0.560
EXOSC10	KPNA5	ENSOARP00000003920	ENSOARP00000009679	Exosome component 10.	Importin subunit alpha; Functions in nuclear protein import.	0.560
EXOSC10	KPNA6	ENSOARP00000003920	ENSOARP00000000638	Exosome component 10.	Importin subunit alpha; Functions in nuclear protein import.	0.560
EXOSC10	KPNB1	ENSOARP00000003920	ENSOARP00000009086	Exosome component 10.	Karyopherin subunit beta 1.	0.937
KPNA1	EXOSC10	ENSOARP00000021625	ENSOARP00000003920	Importin subunit alpha; Functions in nuclear protein import.	Exosome component 10.	0.560
KPNA1	KPNA3	ENSOARP00000021625	ENSOARP00000009249	Importin subunit alpha; Functions in nuclear protein import.	Importin subunit alpha; Functions in nuclear protein import.	0.949
KPNA1	KPNA5	ENSOARP00000021625	ENSOARP00000009679	Importin subunit alpha; Functions in nuclear protein import.	Importin subunit alpha; Functions in nuclear protein import.	0.576
KPNA1	KPNA6	ENSOARP00000021625	ENSOARP00000000638	Importin subunit alpha; Functions in nuclear protein import.	Importin subunit alpha; Functions in nuclear protein import.	0.768
KPNA1	KPNB1	ENSOARP00000021625	ENSOARP00000009086	Importin subunit alpha; Functions in nuclear protein import.	Karyopherin subunit beta 1.	0.991
KPNA1	RAN	ENSOARP00000021625	ENSOARP00000016488	Importin subunit alpha; Functions in nuclear protein import.	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.419
KPNA1	RANBP2	ENSOARP00000021625	ENSOARP00000000590	Importin subunit alpha; Functions in nuclear protein import.	RAN binding protein 2.	0.690
KPNA1	SNUPN	ENSOARP00000021625	ENSOARP00000002094	Importin subunit alpha; Functions in nuclear protein import.	Snurportin 1.	0.416
KPNA3	EXOSC10	ENSOARP00000009249	ENSOARP00000003920	Importin subunit alpha; Functions in nuclear protein import.	Exosome component 10.	0.560
KPNA3	KPNA1	ENSOARP00000009249	ENSOARP00000021625	Importin subunit alpha; Functions in nuclear protein import.	Importin subunit alpha; Functions in nuclear protein import.	0.949
KPNA3	KPNA6	ENSOARP00000009249	ENSOARP00000000638	Importin subunit alpha; Functions in nuclear protein import.	Importin subunit alpha; Functions in nuclear protein import.	0.520
KPNA3	KPNB1	ENSOARP00000009249	ENSOARP00000009086	Importin subunit alpha; Functions in nuclear protein import.	Karyopherin subunit beta 1.	0.939
KPNA3	RAN	ENSOARP00000009249	ENSOARP00000016488	Importin subunit alpha; Functions in nuclear protein import.	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.	0.419
KPNA3	RANBP2	ENSOARP00000009249	ENSOARP00000000590	Importin subunit alpha; Functions in nuclear protein import.	RAN binding protein 2.	0.690