STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HOOK1Hook microtubule tethering protein 1. (733 aa)    
Predicted Functional Partners:
AKTIP
AKT interacting protein.
   
 0.949
FAM160B1
Family with sequence similarity 160 member B1.
    
 0.894
SUN5
Sad1 and UNC84 domain containing 5.
    
 
 0.855
CCDC181
Coiled-coil domain containing 181.
     
 0.837
FAM160A2
Family with sequence similarity 160 member A2.
    
 0.790
SUN3
Sad1 and UNC84 domain containing 3.
    
 
 0.771
HOOK3
Hook microtubule tethering protein 3.
  
 
0.753
HTRA4
HtrA serine peptidase 4.
      
 0.716
FAM160A1
Family with sequence similarity 160 member A1.
    
 0.711
SPACA1
Sperm acrosome associated 1.
      
 0.702
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.