Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| IRF3 | MAP3K7 | ENSOARP00000014293 | ENSOARP00000013207 | Interferon regulatory factor 3. | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. | 0.479 |
| IRF3 | MYD88 | ENSOARP00000014293 | ENSOARP00000001070 | Interferon regulatory factor 3. | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] | 0.902 |
| IRF3 | RIPK1 | ENSOARP00000014293 | ENSOARP00000001620 | Interferon regulatory factor 3. | Receptor interacting serine/threonine kinase 1. | 0.512 |
| IRF3 | TBK1 | ENSOARP00000014293 | ENSOARP00000003587 | Interferon regulatory factor 3. | TANK binding kinase 1. | 0.999 |
| IRF3 | TICAM1 | ENSOARP00000014293 | ENSOARP00000009342 | Interferon regulatory factor 3. | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. | 0.870 |
| IRF3 | TLR3 | ENSOARP00000014293 | ENSOARP00000008645 | Interferon regulatory factor 3. | TIR domain-containing protein; Belongs to the Toll-like receptor family. | 0.913 |
| IRF3 | TLR4 | ENSOARP00000014293 | ENSOARP00000006210 | Interferon regulatory factor 3. | TIR domain-containing protein; Belongs to the Toll-like receptor family. | 0.892 |
| IRF3 | TLR6 | ENSOARP00000014293 | ENSOARP00000000565 | Interferon regulatory factor 3. | Toll-like receptor. | 0.867 |
| IRF3 | TRAF6 | ENSOARP00000014293 | ENSOARP00000020492 | Interferon regulatory factor 3. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.819 |
| MAP3K7 | IRF3 | ENSOARP00000013207 | ENSOARP00000014293 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. | Interferon regulatory factor 3. | 0.479 |
| MAP3K7 | MYD88 | ENSOARP00000013207 | ENSOARP00000001070 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] | 0.997 |
| MAP3K7 | RIPK1 | ENSOARP00000013207 | ENSOARP00000001620 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. | Receptor interacting serine/threonine kinase 1. | 0.834 |
| MAP3K7 | TICAM1 | ENSOARP00000013207 | ENSOARP00000009342 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. | TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. | 0.775 |
| MAP3K7 | TLR3 | ENSOARP00000013207 | ENSOARP00000008645 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. | TIR domain-containing protein; Belongs to the Toll-like receptor family. | 0.960 |
| MAP3K7 | TLR4 | ENSOARP00000013207 | ENSOARP00000006210 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. | TIR domain-containing protein; Belongs to the Toll-like receptor family. | 0.969 |
| MAP3K7 | TRAF6 | ENSOARP00000013207 | ENSOARP00000020492 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.999 |
| MYD88 | IRF3 | ENSOARP00000001070 | ENSOARP00000014293 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] | Interferon regulatory factor 3. | 0.902 |
| MYD88 | MAP3K7 | ENSOARP00000001070 | ENSOARP00000013207 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. | 0.997 |
| MYD88 | RIPK1 | ENSOARP00000001070 | ENSOARP00000001620 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] | Receptor interacting serine/threonine kinase 1. | 0.637 |
| MYD88 | TBK1 | ENSOARP00000001070 | ENSOARP00000003587 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] | TANK binding kinase 1. | 0.823 |
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