STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ATP7BCopper-transporting ATPase 2; Copper ion transmembrane transporter involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile. (1429 aa)    
Predicted Functional Partners:
CCS
Copper chaperone for superoxide dismutase.
  
 0.989
ATOX1
Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity); Belongs to the ATX1 family.
   
 0.976
CP
Ceruloplasmin; Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the cell membrane (By similarity).
  
 
 0.957
LOC101121993
Uncharacterized protein; Belongs to the multicopper oxidase family.
  
 
 0.955
W5PA92_SHEEP
HMA domain-containing protein.
    
 0.918
ATP7A
ATPase copper transporting alpha.
  
  
0.906
COMMD1
Copper metabolism domain containing 1.
    
 
 0.877
COX11
Cytochrome c oxidase copper chaperone COX11.
      
 0.684
SLC30A1
Solute carrier family 30 member 1.
  
  
 0.672
MT4
Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.
      
 0.642
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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