STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLHL28Kelch like family member 28. (578 aa)    
Predicted Functional Partners:
RNF166
Ring finger protein 166.
    
 
 0.847
W5NZ01_SHEEP
Coronin; Belongs to the WD repeat coronin family.
    
 
 0.724
FBXO28
F-box protein 28.
   
  
 0.714
NAA25
N(alpha)-acetyltransferase 25, NatB auxiliary subunit.
      
 0.613
UBE2W
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
 0.609
W5P3W8_SHEEP
RBR-type E3 ubiquitin transferase.
      
 0.569
PRKN
Ubiquitin-like domain-containing protein.
      
 0.569
BBS9
Bardet-Biedl syndrome 9.
    
 0.561
LRSAM1
Leucine rich repeat and sterile alpha motif containing 1.
   
 0.560
BBS1
BBS1 domain-containing protein.
    
 0.558
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.