STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGAP23Rho GTPase activating protein 23. (1411 aa)    
Predicted Functional Partners:
CCDC85C
Coiled-coil domain containing 85C.
    
 
 0.926
CCDC85A
Coiled-coil domain containing 85A.
    
 
 0.920
PPIE
Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
      
 0.600
CDC42
Cell division cycle 42.
   
 0.490
CCDC51
Coiled-coil domain containing 51.
      
 0.467
ZNF541
Zinc finger protein 541.
      
 0.422
RND3
Rho family GTPase 3.
    
 0.411
RND1
Rho family GTPase 1.
    
 0.411
W5P784_SHEEP
Uncharacterized protein.
   
 0.407
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.