STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RND3Rho family GTPase 3. (244 aa)    
Predicted Functional Partners:
ARHGAP5
Rho GTPase activating protein 5.
    
 0.954
ITSN2
Intersectin 2.
    
 0.951
ROCK1
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
   
 0.947
ITSN1
Intersectin 1.
    
 0.915
KCTD10
Potassium channel tetramerization domain containing 10.
    
 0.864
PLEKHG5
Pleckstrin homology and RhoGEF domain containing G5.
    
 0.813
ARHGAP35
Rho GTPase activating protein 35.
    
 0.810
ARHGDIB
Rho GDP dissociation inhibitor beta.
   
 0.795
RBM43
RNA binding motif protein 43.
   
  
 0.783
DOCK4
Dedicator of cytokinesis 4; Belongs to the DOCK family.
   
 0.742
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.