node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CD63 | CD9 | ENSOARP00000012124 | ENSOARP00000009233 | Tetraspanin. | Tetraspanin. | 0.853 |
CD63 | TSG101 | ENSOARP00000012124 | ENSOARP00000010203 | Tetraspanin. | Tumor susceptibility 101. | 0.974 |
CD9 | CD63 | ENSOARP00000009233 | ENSOARP00000012124 | Tetraspanin. | Tetraspanin. | 0.853 |
CD9 | TSG101 | ENSOARP00000009233 | ENSOARP00000010203 | Tetraspanin. | Tumor susceptibility 101. | 0.987 |
HGS | MVB12A | ENSOARP00000019602 | ENSOARP00000017932 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Multivesicular body subunit 12A. | 0.615 |
HGS | MVB12B | ENSOARP00000019602 | ENSOARP00000013532 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Multivesicular body subunit 12B. | 0.655 |
HGS | TSG101 | ENSOARP00000019602 | ENSOARP00000010203 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Tumor susceptibility 101. | 0.996 |
HGS | UBAP1 | ENSOARP00000019602 | ENSOARP00000010011 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Ubiquitin associated protein 1. | 0.438 |
HGS | UBC | ENSOARP00000019602 | ENSOARP00000019508 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Ubiquitin-related; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repa [...] | 0.977 |
HGS | VPS28 | ENSOARP00000019602 | ENSOARP00000014402 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | VPS28 subunit of ESCRT-I; Belongs to the VPS28 family. | 0.796 |
HGS | VPS37A | ENSOARP00000019602 | ENSOARP00000010073 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | VPS37A subunit of ESCRT-I. | 0.595 |
HGS | VPS37B | ENSOARP00000019602 | ENSOARP00000007981 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | VPS37B subunit of ESCRT-I. | 0.720 |
MVB12A | HGS | ENSOARP00000017932 | ENSOARP00000019602 | Multivesicular body subunit 12A. | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | 0.615 |
MVB12A | MVB12B | ENSOARP00000017932 | ENSOARP00000013532 | Multivesicular body subunit 12A. | Multivesicular body subunit 12B. | 0.953 |
MVB12A | TSG101 | ENSOARP00000017932 | ENSOARP00000010203 | Multivesicular body subunit 12A. | Tumor susceptibility 101. | 0.986 |
MVB12A | UBAP1 | ENSOARP00000017932 | ENSOARP00000010011 | Multivesicular body subunit 12A. | Ubiquitin associated protein 1. | 0.920 |
MVB12A | UBC | ENSOARP00000017932 | ENSOARP00000019508 | Multivesicular body subunit 12A. | Ubiquitin-related; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repa [...] | 0.546 |
MVB12A | VPS28 | ENSOARP00000017932 | ENSOARP00000014402 | Multivesicular body subunit 12A. | VPS28 subunit of ESCRT-I; Belongs to the VPS28 family. | 0.998 |
MVB12A | VPS37A | ENSOARP00000017932 | ENSOARP00000010073 | Multivesicular body subunit 12A. | VPS37A subunit of ESCRT-I. | 0.949 |
MVB12A | VPS37B | ENSOARP00000017932 | ENSOARP00000007981 | Multivesicular body subunit 12A. | VPS37B subunit of ESCRT-I. | 0.971 |