STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HOXA1Homeobox A1. (322 aa)    
Predicted Functional Partners:
GDAP1
Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily.
   
  
 0.770
GIPC2
GIPC PDZ domain containing family member 2.
      
 0.661
CLDN14
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
      
 0.609
AEBP2
AE binding protein 2.
    
 
 0.608
ARHGAP12
Rho GTPase activating protein 12.
      
 0.583
CDYL2
Chromodomain Y like 2.
    
 
 0.572
CRIM1
Cysteine rich transmembrane BMP regulator 1.
      
 0.559
GSDME
Gasdermin E.
      
 0.538
KBTBD8
Kelch repeat and BTB domain containing 8.
      
 0.531
SMARCA5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5.
   
 
 0.508
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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