STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5PJH0_SHEEPUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (316 aa)    
Predicted Functional Partners:
TMEM189-UBE2V1
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
 0.947
RAD18
RAD18 E3 ubiquitin protein ligase.
    
 0.903
UBE2Z
Ubiquitin conjugating enzyme E2 Z.
     
 0.841
UBOX5
U-box domain containing 5.
    
 0.831
UBA6
Ubiquitin like modifier activating enzyme 6.
   
 0.786
UBA7
Ubiquitin like modifier activating enzyme 7.
   
 0.786
UBA1
Ubiquitin like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family.
   
 0.786
UBE2V2
Ubiquitin conjugating enzyme E2 V2.
   
 0.777
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.772
RPS27A
Ubiquitin-like domain-containing protein.
   
 0.768
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.