STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZEB2Zinc finger E-box binding homeobox 2. (1193 aa)    
Predicted Functional Partners:
ZEB1
Zinc finger E-box binding homeobox 1.
     
0.911
TWIST1
Twist family bHLH transcription factor 1.
     
 0.781
TWIST2
Twist family bHLH transcription factor 2.
     
 0.744
CDH2
Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.
  
  
 0.738
SNAI1
Snail family transcriptional repressor 1.
      
0.694
VIM
Vimentin; Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.
      
 0.681
CTBP2
Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
 
 0.668
W5Q3P0_SHEEP
Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
 
 0.666
SMAD2
Mothers against decapentaplegic homolog.
   
 
 0.659
SNAI2
Snai2.
      
0.651
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.