STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABHD16BAbhydrolase domain containing 16B. (451 aa)    
Predicted Functional Partners:
NPBWR2
Neuropeptides B and W receptor 2; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.931
GJA3
Gap junction alpha-3 protein.
   
  
 0.864
IFT81
Intraflagellar transport 81.
      
 0.833
CSRP1
Cysteine and glycine rich protein 1.
   
  
 0.830
GJB6
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.780
TNNI1
Troponin I1, slow skeletal type.
      
 0.738
LATS2
Large tumor suppressor kinase 2.
      
 0.654
GJB2
Gap junction beta-2 protein; Structural component of gap junctions (By similarity). Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane (By similarity). Small molecules and ions diffuse from one cell to a neighboring cell via the central pore (By similarity).
      
 0.643
ARMC3
Armadillo repeat containing 3.
      
 0.614
FNDC11
Fibronectin type III domain containing 11.
      
 0.613
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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