STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGFLAMEGF like, fibronectin type III and laminin G domains. (1026 aa)    
Predicted Functional Partners:
DAG1
Dystroglycan 1.
   
 0.822
LRIT3
Leucine rich repeat, Ig-like and transmembrane domains 3.
    
 0.803
ZNF250
KRAB domain-containing protein.
   
 0.745
SERTM1
Serine rich and transmembrane domain containing 1.
      
 0.741
TMEM164
Transmembrane protein 164.
      
 0.735
NYX
Nyctalopin.
   
 0.710
TMEM14A
Transmembrane protein 14A.
      
 0.680
USH2A
Usherin.
    
0.644
WHRN
Whirlin.
    
 
 0.624
CRHBP
Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy; Belongs to the CRF-binding protein family.
      
 0.612
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.