STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MX2Interferon-induced GTP-binding protein Mx2; Interferon-induced dynamin-like GTPase with antiviral activity. (713 aa)    
Predicted Functional Partners:
ISG15
Uncharacterized protein.
   
 0.998
MX1
Interferon-induced GTP-binding protein Mx1; Interferon-induced dynamin-like GTPase with antiviral activity.
  
 
0.998
EIF2AK2
Eukaryotic translation initiation factor 2 alpha kinase 2.
   
 0.975
TRIM21
Tripartite motif containing 21.
   
 
 0.941
RSAD2
Radical S-adenosyl methionine domain containing 2.
   
  
 0.941
CXCL10
C-X-C motif chemokine.
   
  
 0.894
LOC101103965
USP domain-containing protein; Belongs to the peptidase C19 family.
   
 0.888
GAK
Cyclin G associated kinase.
   
 0.884
IFIT1
Interferon induced protein with tetratricopeptide repeats 1.
   
 
 0.856
IFIT3
Interferon induced protein with tetratricopeptide repeats 3.
   
 
 0.850
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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