STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PARP11Poly [ADP-ribose] polymerase. (380 aa)    
Predicted Functional Partners:
PARP2
Poly [ADP-ribose] polymerase.
      
 0.778
ALPL
Alkaline phosphatase.
      
 0.616
PARP6
Poly [ADP-ribose] polymerase.
      
 0.538
PARP8
Poly [ADP-ribose] polymerase.
      
 0.517
PARP4
Poly [ADP-ribose] polymerase.
      
 0.516
XRCC4
X-ray repair cross complementing 4.
    
 
 0.491
PDE6G
Phosphodiesterase 6G.
      
 0.478
PARG
Poly(ADP-ribose) glycohydrolase.
      
 0.457
USP50
Ubiquitin specific peptidase 50; Belongs to the peptidase C19 family.
      
 0.433
PARP16
Poly [ADP-ribose] polymerase.
      
 0.426
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (18%) [HD]