STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACTL8Actin like 8; Belongs to the actin family. (362 aa)    
Predicted Functional Partners:
ACTR10
Actin related protein 10; Belongs to the actin family.
   
0.864
DCTN4
Dynactin subunit 4.
   
 0.855
DCTN2
Dynactin subunit 2.
   
 0.848
DCTN6
Dynactin subunit 6.
    
 0.822
ACTR8
Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily.
    
 0.789
RUVBL1
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
   
 0.775
ACTR1A
Actin related protein 1A.
    
  
0.749
ACTR1B
Actin related protein 1B.
    
  
0.749
MYO1C
Myosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 0.748
ACTL6B
Actin like 6B; Belongs to the actin family.
    
0.720
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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