Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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[Homology]
Score
TMPRSS3Transmembrane serine protease 3; Belongs to the peptidase S1 family. (532 aa)    
Predicted Functional Partners:
BOP1
BOP1 ribosomal biogenesis factor.
      
 0.793
LOC101103343
Uncharacterized protein.
    
 0.766
TMIE
Transmembrane inner ear.
      
 0.605
UBASH3A
Ubiquitin associated and SH3 domain containing A.
   
  
 0.583
UMODL1
Uromodulin like 1.
    
 0.580
LOC101120999
C-type lectin domain-containing protein.
   
 0.579
FAM169A
Family with sequence similarity 169 member A.
    
 0.570
TTC23
Tetratricopeptide repeat domain 23.
    
 
 0.551
TMEM232
Transmembrane protein 232.
      
 0.550
HEATR5B
HEAT repeat containing 5B.
      
 0.546
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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