| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CER1 | WNT9B | ENSOARP00000014923 | ENSOARP00000011554 | Cerberus 1, DAN family BMP antagonist. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.913 |
| FZD3 | FZD4 | ENSOARP00000016064 | ENSOARP00000004465 | Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.581 |
| FZD3 | LRP6 | ENSOARP00000016064 | ENSOARP00000022437 | Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.954 |
| FZD3 | WNT4 | ENSOARP00000016064 | ENSOARP00000008664 | Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.714 |
| FZD3 | WNT9B | ENSOARP00000016064 | ENSOARP00000011554 | Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.872 |
| FZD4 | FZD3 | ENSOARP00000004465 | ENSOARP00000016064 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. | Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.581 |
| FZD4 | LRP6 | ENSOARP00000004465 | ENSOARP00000022437 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.992 |
| FZD4 | WNT4 | ENSOARP00000004465 | ENSOARP00000008664 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.745 |
| FZD4 | WNT9B | ENSOARP00000004465 | ENSOARP00000011554 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.868 |
| GPC3 | NOTUM | ENSOARP00000013058 | ENSOARP00000018986 | Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. | Notum, palmitoleoyl-protein carboxylesterase. | 0.759 |
| GPC3 | WNT9B | ENSOARP00000013058 | ENSOARP00000011554 | Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.911 |
| LRP6 | FZD3 | ENSOARP00000022437 | ENSOARP00000016064 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.954 |
| LRP6 | FZD4 | ENSOARP00000022437 | ENSOARP00000004465 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.992 |
| LRP6 | PORCN | ENSOARP00000022437 | ENSOARP00000013312 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Porcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family. | 0.437 |
| LRP6 | WIF1 | ENSOARP00000022437 | ENSOARP00000003323 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | WNT inhibitory factor 1. | 0.480 |
| LRP6 | WNT4 | ENSOARP00000022437 | ENSOARP00000008664 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.838 |
| LRP6 | WNT9B | ENSOARP00000022437 | ENSOARP00000011554 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.877 |
| NOTUM | GPC3 | ENSOARP00000018986 | ENSOARP00000013058 | Notum, palmitoleoyl-protein carboxylesterase. | Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. | 0.759 |
| NOTUM | WIF1 | ENSOARP00000018986 | ENSOARP00000003323 | Notum, palmitoleoyl-protein carboxylesterase. | WNT inhibitory factor 1. | 0.551 |
| NOTUM | WLS | ENSOARP00000018986 | ENSOARP00000012200 | Notum, palmitoleoyl-protein carboxylesterase. | Wnt ligand secretion mediator. | 0.491 |
