STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAB35RAB35, member RAS oncogene family. (202 aa)    
Predicted Functional Partners:
DENND1B
DENN domain containing 1B.
    
 0.969
DENND1C
DENN domain containing 1C.
    
 0.932
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2.
    
 
 0.931
GDI1
Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.
    
 0.889
DENND1A
UDENN domain-containing protein.
    
 0.879
TBC1D10A
TBC1 domain family member 10A.
   
 0.877
RUSC2
RUN and SH3 domain containing 2.
    
 
 0.871
GDI2
Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.
    
 0.857
W5PWB4_SHEEP
UDENN domain-containing protein.
    
 0.857
RILPL2
Rab interacting lysosomal protein like 2.
      
 0.831
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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