RAB35 protein (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DENND1A	DENND1B	ENSOARP00000014765	ENSOARP00000016463	UDENN domain-containing protein.	DENN domain containing 1B.	0.692
DENND1A	DENND1C	ENSOARP00000014765	ENSOARP00000006012	UDENN domain-containing protein.	DENN domain containing 1C.	0.538
DENND1A	RAB35	ENSOARP00000014765	ENSOARP00000011802	UDENN domain-containing protein.	RAB35, member RAS oncogene family.	0.873
DENND1B	DENND1A	ENSOARP00000016463	ENSOARP00000014765	DENN domain containing 1B.	UDENN domain-containing protein.	0.692
DENND1B	DENND1C	ENSOARP00000016463	ENSOARP00000006012	DENN domain containing 1B.	DENN domain containing 1C.	0.436
DENND1B	RAB35	ENSOARP00000016463	ENSOARP00000011802	DENN domain containing 1B.	RAB35, member RAS oncogene family.	0.915
DENND1C	DENND1A	ENSOARP00000006012	ENSOARP00000014765	DENN domain containing 1C.	UDENN domain-containing protein.	0.538
DENND1C	DENND1B	ENSOARP00000006012	ENSOARP00000016463	DENN domain containing 1C.	DENN domain containing 1B.	0.436
DENND1C	RAB10	ENSOARP00000006012	ENSOARP00000019880	DENN domain containing 1C.	Uncharacterized protein.	0.579
DENND1C	RAB35	ENSOARP00000006012	ENSOARP00000011802	DENN domain containing 1C.	RAB35, member RAS oncogene family.	0.876
GDI1	RAB10	ENSOARP00000004948	ENSOARP00000019880	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	Uncharacterized protein.	0.858
GDI1	RAB35	ENSOARP00000004948	ENSOARP00000011802	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	RAB35, member RAS oncogene family.	0.938
GDI2	RAB10	ENSOARP00000008686	ENSOARP00000019880	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	Uncharacterized protein.	0.847
GDI2	RAB35	ENSOARP00000008686	ENSOARP00000011802	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	RAB35, member RAS oncogene family.	0.915
RAB10	DENND1C	ENSOARP00000019880	ENSOARP00000006012	Uncharacterized protein.	DENN domain containing 1C.	0.579
RAB10	GDI1	ENSOARP00000019880	ENSOARP00000004948	Uncharacterized protein.	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.858
RAB10	GDI2	ENSOARP00000019880	ENSOARP00000008686	Uncharacterized protein.	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.847
RAB10	RAB35	ENSOARP00000019880	ENSOARP00000011802	Uncharacterized protein.	RAB35, member RAS oncogene family.	0.929
RAB10	RILPL2	ENSOARP00000019880	ENSOARP00000003887	Uncharacterized protein.	Rab interacting lysosomal protein like 2.	0.963
RAB35	DENND1A	ENSOARP00000011802	ENSOARP00000014765	RAB35, member RAS oncogene family.	UDENN domain-containing protein.	0.873