STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RDH5Retinol dehydrogenase 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (304 aa)    
Predicted Functional Partners:
RPE65
Retinoid isomerohydrolase RPE65.
   
 
 0.978
LRAT
LRAT domain-containing protein.
     
 0.978
ALDH1A1
Retinal dehydrogenase 1; Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo.
   
 
 0.937
W5PIK8_SHEEP
LRAT domain-containing protein.
     
 0.932
RDH10
Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
0.929
ALDH1A3
Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family.
   
 
 0.928
RDH11
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
0.927
RDH12
Retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.924
ALDH1A2
Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family.
   
 
 0.907
AWAT2
Acyl-CoA wax alcohol acyltransferase 2.
   
 
  0.905
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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