STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPEF2Sperm flagellar 2. (1819 aa)    
Predicted Functional Partners:
SPAG6
Sperm associated antigen 6.
   
 0.901
CMTM2
CKLF like MARVEL transmembrane domain containing 2.
      
 0.842
DNAI1
Dynein axonemal intermediate chain 1.
   
  
 0.839
EFCAB6
EF-hand calcium binding domain 6.
   
  0.796
CIB4
Calcium and integrin-binding family member 4.
    
 0.754
SPEF1
Sperm flagellar 1.
   
 
 0.753
CCDC40
Coiled-coil domain containing 40.
    
 0.746
LRGUK
Leucine rich repeats and guanylate kinase domain containing.
   
 0.741
SSMEM1
Serine rich single-pass membrane protein 1.
      
 0.704
SOX5
SRY-box transcription factor 5.
    
 
 0.687
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.