Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
JCHAINJoining chain of multimeric IgA and IgM. (159 aa)    
Predicted Functional Partners:
PIGR
Polymeric immunoglobulin receptor.
  
 
 0.988
MZB1
Marginal zone B and B1 cell specific protein.
   
  
 0.958
PIGA
Phosphatidylinositol glycan anchor biosynthesis class A.
      
 0.898
FCMR
Fc fragment of IgM receptor.
   
 
 0.879
W5NV16_SHEEP
Ig-like domain-containing protein.
   
 
 0.823
W5PAL4_SHEEP
Uncharacterized protein.
   
 0.815
CD79A
CD79a molecule.
   
 
 0.811
TXNDC5
Thioredoxin domain containing 5.
   
  
 0.811
POU2AF1
POU class 2 homeobox associating factor 1.
   
  
 0.796
CD79B
CD79b molecule.
   
 
 0.786
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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