STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5PPR7_SHEEPATP-grasp domain-containing protein. (839 aa)    
Predicted Functional Partners:
PPP1R18
Protein phosphatase 1 regulatory subunit 18.
      
 0.888
NPDC1
Uncharacterized protein.
      
 0.836
COLGALT2
Collagen beta(1-O)galactosyltransferase 2.
      
 0.823
RPS6KB2
Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
   
  
 0.755
GGT5
Gamma-glutamyltransferase 5.
    
 
 0.702
DPEP1
Dipeptidase 1; Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity. In lung tissue, it may terminate or significantly reduce the leukotriene induced signal for bronchospasm.
      
 0.684
MCHR1
Melanin concentrating hormone receptor 1.
      
 0.677
CNDP1
Carnosine dipeptidase 1.
  
  
 0.629
NCOR2
Nuclear receptor corepressor 2.
      
 0.615
CARNMT1
Carnosine N-methyltransferase 1.
      
 0.611
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.