GPS2 protein (Ovis aries) - STRING interaction network

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Predicted Interactions

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Score

GPS2

G protein pathway suppressor 2. (327 aa)

Predicted Functional Partners:

HDAC3

0.945

W5PJG1_SHEEP

0.929

TBL1XR1

0.907

NCOR1

0.868

TAF9B

0.829

TAF12

0.828

TADA3

0.828

TAF10

0.818

TRRAP

0.814

NR1D1

0.810

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GPS2	HDAC3	ENSOARP00000012645	ENSOARP00000000868	G protein pathway suppressor 2.	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.945
GPS2	NCOR1	ENSOARP00000012645	ENSOARP00000018408	G protein pathway suppressor 2.	Nuclear receptor corepressor 1.	0.868
GPS2	NR1D1	ENSOARP00000012645	ENSOARP00000013954	G protein pathway suppressor 2.	Nuclear receptor subfamily 1 group D member 1; Transcriptional repressor which coordinates circadian rhythm and metabolic pathways in a heme-dependent manner. Integral component of the complex transcription machinery that governs circadian rhythmicity and forms a critical negative limb of the circadian clock by directly repressing the expression of core clock components ARTNL/BMAL1, CLOCK and CRY1. Also regulates genes involved in metabolic functions, including lipid and bile acid metabolism, adipogenesis, gluconeogenesis and the macrophage inflammatory response. Acts as a receptor for [...]	0.810
GPS2	TADA3	ENSOARP00000012645	ENSOARP00000006590	G protein pathway suppressor 2.	Transcriptional adaptor 3.	0.828
GPS2	TAF10	ENSOARP00000012645	ENSOARP00000018441	G protein pathway suppressor 2.	TATA-box binding protein associated factor 10.	0.818
GPS2	TAF12	ENSOARP00000012645	ENSOARP00000003003	G protein pathway suppressor 2.	TATA-box binding protein associated factor 12.	0.828
GPS2	TAF9B	ENSOARP00000012645	ENSOARP00000020252	G protein pathway suppressor 2.	TATA-box binding protein associated factor 9b.	0.829
GPS2	TBL1XR1	ENSOARP00000012645	ENSOARP00000022267	G protein pathway suppressor 2.	Transducin beta like 1 X-linked receptor 1.	0.907
GPS2	TRRAP	ENSOARP00000012645	ENSOARP00000000357	G protein pathway suppressor 2.	Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family.	0.814
GPS2	W5PJG1_SHEEP	ENSOARP00000012645	ENSOARP00000010582	G protein pathway suppressor 2.	Uncharacterized protein.	0.929
HDAC3	GPS2	ENSOARP00000000868	ENSOARP00000012645	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	G protein pathway suppressor 2.	0.945
HDAC3	NCOR1	ENSOARP00000000868	ENSOARP00000018408	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Nuclear receptor corepressor 1.	0.998
HDAC3	NR1D1	ENSOARP00000000868	ENSOARP00000013954	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Nuclear receptor subfamily 1 group D member 1; Transcriptional repressor which coordinates circadian rhythm and metabolic pathways in a heme-dependent manner. Integral component of the complex transcription machinery that governs circadian rhythmicity and forms a critical negative limb of the circadian clock by directly repressing the expression of core clock components ARTNL/BMAL1, CLOCK and CRY1. Also regulates genes involved in metabolic functions, including lipid and bile acid metabolism, adipogenesis, gluconeogenesis and the macrophage inflammatory response. Acts as a receptor for [...]	0.600
HDAC3	TBL1XR1	ENSOARP00000000868	ENSOARP00000022267	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Transducin beta like 1 X-linked receptor 1.	0.898
HDAC3	TRRAP	ENSOARP00000000868	ENSOARP00000000357	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family.	0.444
HDAC3	W5PJG1_SHEEP	ENSOARP00000000868	ENSOARP00000010582	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Uncharacterized protein.	0.922
NCOR1	GPS2	ENSOARP00000018408	ENSOARP00000012645	Nuclear receptor corepressor 1.	G protein pathway suppressor 2.	0.868
NCOR1	HDAC3	ENSOARP00000018408	ENSOARP00000000868	Nuclear receptor corepressor 1.	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.998
NCOR1	NR1D1	ENSOARP00000018408	ENSOARP00000013954	Nuclear receptor corepressor 1.	Nuclear receptor subfamily 1 group D member 1; Transcriptional repressor which coordinates circadian rhythm and metabolic pathways in a heme-dependent manner. Integral component of the complex transcription machinery that governs circadian rhythmicity and forms a critical negative limb of the circadian clock by directly repressing the expression of core clock components ARTNL/BMAL1, CLOCK and CRY1. Also regulates genes involved in metabolic functions, including lipid and bile acid metabolism, adipogenesis, gluconeogenesis and the macrophage inflammatory response. Acts as a receptor for [...]	0.937
NCOR1	TADA3	ENSOARP00000018408	ENSOARP00000006590	Nuclear receptor corepressor 1.	Transcriptional adaptor 3.	0.868