STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MEDAGMesenteric estrogen dependent adipogenesis. (303 aa)    
Predicted Functional Partners:
OPN5
Opsin 5; Belongs to the G-protein coupled receptor 1 family.
      
 0.853
B3GLCT
Beta 3-glucosyltransferase.
      
 0.811
ALOX5AP
Arachidonate 5-lipoxygenase-activating protein; Required for leukotriene biosynthesis by ALOX5 (5- lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes (By similarity); Belongs to the MAPEG family.
      
 0.778
PRDM5
Zinc finger protein.
      
 0.731
DGKI
Diacylglycerol kinase.
      
 0.728
PTPRT
Uncharacterized protein.
      
 0.663
ZC2HC1C
Zinc finger C2HC-type containing 1C.
      
 0.538
SLC7A14
Solute carrier family 7 member 14.
      
 0.538
W5P6Y4_SHEEP
Uncharacterized protein.
      
 0.521
DACT1
Dishevelled binding antagonist of beta catenin 1.
      
 0.506
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.