STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FBXL4F-box and leucine rich repeat protein 4. (621 aa)    
Predicted Functional Partners:
ZIM3
KRAB domain-containing protein.
   
 
 0.828
SINHCAF
SIN3-HDAC complex associated factor.
      
 0.821
ZNF641
Zinc finger protein 641.
   
 
 0.757
DEF8
Differentially expressed in FDCP 8 homolog.
      
 0.686
ZNF79
Zinc finger protein 79.
   
 
 0.665
RBX1
Ring-box 1.
    
 0.657
RSC1A1
Regulator of solute carriers 1.
      
 0.656
NEDD8
NEDD8 ubiquitin like modifier.
    
 0.646
KLHL32
Kelch like family member 32.
     
 0.645
W5PEG8_SHEEP
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.641
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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