STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SKA2Spindle and kinetochore associated complex subunit 2. (120 aa)    
Predicted Functional Partners:
SKA3
Spindle and kinetochore associated complex subunit 3.
   
 0.992
SKA1
Spindle and kinetochore associated complex subunit 1.
   
 0.990
PLK1
Serine/threonine-protein kinase PLK.
   
 
 0.968
NUDC
Nuclear distribution C, dynein complex regulator.
     
 0.913
KIAA0930
KIAA0930.
      
 0.855
CDC20
Cell division cycle 20.
     
 0.800
ARPP21
cAMP regulated phosphoprotein 21.
      
 0.796
CDC20B
Cell division cycle 20B.
     
 0.780
OTULIN
OTU deubiquitinase with linear linkage specificity.
      
 0.762
CTDSP1
CTD small phosphatase 1.
      
 0.736
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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