node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACE2 | AGT | ENSOARP00000013345 | ENSOARP00000003247 | Angiotensin-converting enzyme. | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family. | 0.991 |
ACE2 | AGTR1 | ENSOARP00000013345 | ENSOARP00000016502 | Angiotensin-converting enzyme. | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. | 0.921 |
ACE2 | DPP4 | ENSOARP00000013345 | ENSOARP00000006914 | Angiotensin-converting enzyme. | Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. | 0.990 |
ACE2 | MEP1A | ENSOARP00000013345 | ENSOARP00000012032 | Angiotensin-converting enzyme. | Meprin A subunit. | 0.933 |
ACE2 | MEP1B | ENSOARP00000013345 | ENSOARP00000006526 | Angiotensin-converting enzyme. | Meprin A subunit. | 0.926 |
ACE2 | MME | ENSOARP00000013345 | ENSOARP00000003611 | Angiotensin-converting enzyme. | Membrane metalloendopeptidase. | 0.993 |
ACE2 | PRCP | ENSOARP00000013345 | ENSOARP00000006230 | Angiotensin-converting enzyme. | Prolylcarboxypeptidase. | 0.958 |
ACE2 | REN | ENSOARP00000013345 | ENSOARP00000002426 | Angiotensin-converting enzyme. | Renin; Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. | 0.984 |
ACE2 | TMPRSS2 | ENSOARP00000013345 | ENSOARP00000011088 | Angiotensin-converting enzyme. | Transmembrane serine protease 2; Belongs to the peptidase S1 family. | 0.959 |
ACE2 | XPNPEP2 | ENSOARP00000013345 | ENSOARP00000016045 | Angiotensin-converting enzyme. | X-prolyl aminopeptidase 2; Belongs to the peptidase M24B family. | 0.910 |
AGT | ACE2 | ENSOARP00000003247 | ENSOARP00000013345 | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family. | Angiotensin-converting enzyme. | 0.991 |
AGT | AGTR1 | ENSOARP00000003247 | ENSOARP00000016502 | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family. | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. | 0.999 |
AGT | DPP4 | ENSOARP00000003247 | ENSOARP00000006914 | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family. | Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. | 0.509 |
AGT | MME | ENSOARP00000003247 | ENSOARP00000003611 | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family. | Membrane metalloendopeptidase. | 0.919 |
AGT | PRCP | ENSOARP00000003247 | ENSOARP00000006230 | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family. | Prolylcarboxypeptidase. | 0.512 |
AGT | REN | ENSOARP00000003247 | ENSOARP00000002426 | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family. | Renin; Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. | 0.994 |
AGT | TMPRSS2 | ENSOARP00000003247 | ENSOARP00000011088 | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family. | Transmembrane serine protease 2; Belongs to the peptidase S1 family. | 0.589 |
AGTR1 | ACE2 | ENSOARP00000016502 | ENSOARP00000013345 | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. | Angiotensin-converting enzyme. | 0.921 |
AGTR1 | AGT | ENSOARP00000016502 | ENSOARP00000003247 | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. | Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family. | 0.999 |
AGTR1 | MME | ENSOARP00000016502 | ENSOARP00000003611 | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. | Membrane metalloendopeptidase. | 0.436 |