STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GYS1Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (755 aa)    
Predicted Functional Partners:
GYG1
Glycogenin 1.
   
 0.999
GBE1
1,4-alpha-glucan branching enzyme 1.
   
 0.999
PPP1R3C
Protein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown.
   
 0.996
PPP1R3D
Protein phosphatase 1 regulatory subunit.
   
 0.974
PPP1R3B
Protein phosphatase 1 regulatory subunit.
   
 0.970
UGP2
UTP--glucose-1-phosphate uridylyltransferase.
   
 
 0.969
PPP1R3A
Protein phosphatase 1 regulatory subunit 3A.
   
 0.962
PRKAG2
Protein kinase AMP-activated non-catalytic subunit gamma 2.
   
 
 0.952
AGL
Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase.
  
 0.948
GSK3B
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.946
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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