STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FZR1WD_REPEATS_REGION domain-containing protein. (493 aa)    
Predicted Functional Partners:
CDC23
Cell division cycle 23.
   
 0.992
CDC27
Cell division cycle 27.
   
 0.988
MAD2L1
Mitotic arrest deficient 2 like 1.
   
 0.988
CDC16
Cell division cycle 16.
   
 0.987
ANAPC4
Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family.
   
 0.984
ANAPC5
Anaphase promoting complex subunit 5.
    
 0.981
ANAPC1
Anaphase promoting complex subunit 1.
    
 0.974
MAD1L1
Uncharacterized protein.
   
 0.973
ANAPC7
Anaphase promoting complex subunit 7.
    
 0.973
ANAPC2-2
Uncharacterized protein.
   
 0.971
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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