| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BTRC | EP300 | ENSOARP00000017683 | ENSOARP00000019268 | Beta-transducin repeat containing E3 ubiquitin protein ligase. | E1A binding protein p300. | 0.402 |
| BTRC | GSK3B | ENSOARP00000017683 | ENSOARP00000021297 | Beta-transducin repeat containing E3 ubiquitin protein ligase. | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. | 0.859 |
| BTRC | SNAI1 | ENSOARP00000017683 | ENSOARP00000014113 | Beta-transducin repeat containing E3 ubiquitin protein ligase. | Snail family transcriptional repressor 1. | 0.938 |
| BTRC | TP53 | ENSOARP00000017683 | ENSOARP00000016707 | Beta-transducin repeat containing E3 ubiquitin protein ligase. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.692 |
| BTRC | TWIST1 | ENSOARP00000017683 | ENSOARP00000010457 | Beta-transducin repeat containing E3 ubiquitin protein ligase. | Twist family bHLH transcription factor 1. | 0.671 |
| CREBBP | EP300 | ENSOARP00000002661 | ENSOARP00000019268 | CREB binding protein. | E1A binding protein p300. | 0.999 |
| CREBBP | KDM1A | ENSOARP00000002661 | ENSOARP00000008285 | CREB binding protein. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.594 |
| CREBBP | SNAI1 | ENSOARP00000002661 | ENSOARP00000014113 | CREB binding protein. | Snail family transcriptional repressor 1. | 0.823 |
| CREBBP | TP53 | ENSOARP00000002661 | ENSOARP00000016707 | CREB binding protein. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.997 |
| DNMT1 | EP300 | ENSOARP00000016508 | ENSOARP00000019268 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | E1A binding protein p300. | 0.406 |
| DNMT1 | KDM1A | ENSOARP00000016508 | ENSOARP00000008285 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.914 |
| DNMT1 | RCOR1 | ENSOARP00000016508 | ENSOARP00000005247 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | REST corepressor 1. | 0.406 |
| DNMT1 | SNAI1 | ENSOARP00000016508 | ENSOARP00000014113 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Snail family transcriptional repressor 1. | 0.860 |
| DNMT1 | TP53 | ENSOARP00000016508 | ENSOARP00000016707 | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.859 |
| EP300 | BTRC | ENSOARP00000019268 | ENSOARP00000017683 | E1A binding protein p300. | Beta-transducin repeat containing E3 ubiquitin protein ligase. | 0.402 |
| EP300 | CREBBP | ENSOARP00000019268 | ENSOARP00000002661 | E1A binding protein p300. | CREB binding protein. | 0.999 |
| EP300 | DNMT1 | ENSOARP00000019268 | ENSOARP00000016508 | E1A binding protein p300. | DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.406 |
| EP300 | KDM1A | ENSOARP00000019268 | ENSOARP00000008285 | E1A binding protein p300. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.778 |
| EP300 | SNAI1 | ENSOARP00000019268 | ENSOARP00000014113 | E1A binding protein p300. | Snail family transcriptional repressor 1. | 0.857 |
| EP300 | TP53 | ENSOARP00000019268 | ENSOARP00000016707 | E1A binding protein p300. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.998 |
