NMB protein (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NMB

Neuromedin B. (152 aa)

Predicted Functional Partners:

NMBR

0.998

GRPR

0.997

BRS3

0.979

GRP

0.976

ELP3

0.870

SGCE

0.866

SGCA

0.866

NMS

0.844

NPFF

0.809

W5P7E0_SHEEP

0.757

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRS3	GRP	ENSOARP00000012091	ENSOARP00000004291	Bombesin receptor subtype-3; Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).	Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake (By similarity); Belongs to the bombesin/neuromedin-B/ranatensin family.	0.980
BRS3	GRPR	ENSOARP00000012091	ENSOARP00000013733	Bombesin receptor subtype-3; Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).	Gastrin releasing peptide receptor.	0.942
BRS3	NMB	ENSOARP00000012091	ENSOARP00000014121	Bombesin receptor subtype-3; Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).	Neuromedin B.	0.979
BRS3	NMBR	ENSOARP00000012091	ENSOARP00000001338	Bombesin receptor subtype-3; Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).	Neuromedin B receptor; Belongs to the G-protein coupled receptor 1 family.	0.936
BRS3	NMS	ENSOARP00000012091	ENSOARP00000014263	Bombesin receptor subtype-3; Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).	Neuromedin S.	0.422
ELP3	NMB	ENSOARP00000015996	ENSOARP00000014121	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	Neuromedin B.	0.870
GRP	BRS3	ENSOARP00000004291	ENSOARP00000012091	Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake (By similarity); Belongs to the bombesin/neuromedin-B/ranatensin family.	Bombesin receptor subtype-3; Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).	0.980
GRP	GRPR	ENSOARP00000004291	ENSOARP00000013733	Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake (By similarity); Belongs to the bombesin/neuromedin-B/ranatensin family.	Gastrin releasing peptide receptor.	0.996
GRP	NMB	ENSOARP00000004291	ENSOARP00000014121	Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake (By similarity); Belongs to the bombesin/neuromedin-B/ranatensin family.	Neuromedin B.	0.976
GRP	NMBR	ENSOARP00000004291	ENSOARP00000001338	Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake (By similarity); Belongs to the bombesin/neuromedin-B/ranatensin family.	Neuromedin B receptor; Belongs to the G-protein coupled receptor 1 family.	0.964
GRP	NMS	ENSOARP00000004291	ENSOARP00000014263	Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake (By similarity); Belongs to the bombesin/neuromedin-B/ranatensin family.	Neuromedin S.	0.619
GRP	NPFF	ENSOARP00000004291	ENSOARP00000017634	Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake (By similarity); Belongs to the bombesin/neuromedin-B/ranatensin family.	Neuropeptide FF-amide peptide precursor.	0.574
GRPR	BRS3	ENSOARP00000013733	ENSOARP00000012091	Gastrin releasing peptide receptor.	Bombesin receptor subtype-3; Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).	0.942
GRPR	GRP	ENSOARP00000013733	ENSOARP00000004291	Gastrin releasing peptide receptor.	Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake (By similarity); Belongs to the bombesin/neuromedin-B/ranatensin family.	0.996
GRPR	NMB	ENSOARP00000013733	ENSOARP00000014121	Gastrin releasing peptide receptor.	Neuromedin B.	0.997
GRPR	NMBR	ENSOARP00000013733	ENSOARP00000001338	Gastrin releasing peptide receptor.	Neuromedin B receptor; Belongs to the G-protein coupled receptor 1 family.	0.937
GRPR	NMS	ENSOARP00000013733	ENSOARP00000014263	Gastrin releasing peptide receptor.	Neuromedin S.	0.457
NMB	BRS3	ENSOARP00000014121	ENSOARP00000012091	Neuromedin B.	Bombesin receptor subtype-3; Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).	0.979
NMB	ELP3	ENSOARP00000014121	ENSOARP00000015996	Neuromedin B.	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	0.870
NMB	GRP	ENSOARP00000014121	ENSOARP00000004291	Neuromedin B.	Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake (By similarity); Belongs to the bombesin/neuromedin-B/ranatensin family.	0.976