STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDH15Cadherin 15; Cadherins are calcium-dependent cell adhesion proteins. (769 aa)    
Predicted Functional Partners:
TM6SF1
Transmembrane 6 superfamily member 1.
   
  
 0.931
TMEM182
Transmembrane protein 182.
      
 0.782
CTNNB1
Catenin beta 1.
   
 0.781
CTNND1
Catenin delta 1.
    
 0.778
JUP
Junction plakoglobin.
   
 0.745
ABLIM3
Actin binding LIM protein family member 3.
      
 0.654
W5Q9A6_SHEEP
Uncharacterized protein.
    
 0.652
TENM4
Uncharacterized protein.
   
  
 0.645
TSPAN33
Tetraspanin.
     
 0.638
KCNQ5
Potassium voltage-gated channel subfamily Q member 5; Belongs to the potassium channel family.
    
 
 0.623
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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