STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CIAO1Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. (339 aa)    
Predicted Functional Partners:
CIAO2B
Cytosolic iron-sulfur assembly component 2B.
    
 0.994
MMS19
MMS19 homolog, cytosolic iron-sulfur assembly component.
    
 0.989
GBF1
Golgi brefeldin A resistant guanine nucleotide exchange factor 1.
      
 0.971
W5P364_SHEEP
FeS_assembly_P domain-containing protein.
    
 0.920
CIAO2A
FeS_assembly_P domain-containing protein.
    
 0.920
CIAO3
Cytosolic iron-sulfur assembly component 3; Belongs to the NARF family.
    
 0.899
DCAF10
DDB1 and CUL4 associated factor 10.
    
 
 0.889
CYP20A1
Cytochrome P450 family 20 subfamily A member 1.
      
 0.878
C17orf75
Chromosome 17 open reading frame 75.
      
 0.875
SYNJ2BP
PDZ domain-containing protein.
      
 0.872
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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