STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLCA4Chloride channel accessory 4. (949 aa)    
Predicted Functional Partners:
TMCC3
Transmembrane and coiled-coil domain family 3.
     
 0.823
TMTC4
Transmembrane O-mannosyltransferase targeting cadherins 4.
    
 0.758
ZG16
Zymogen granule protein 16.
   
  
 0.705
KRT24
Keratin 24; Belongs to the intermediate filament family.
   
 0.627
CRNN
Cornulin.
   
 0.624
TMTC2
Transmembrane O-mannosyltransferase targeting cadherins 2.
    
 0.621
MSI1
Musashi RNA binding protein 1.
    
 
 0.615
DACH1
Uncharacterized protein.
      
 0.600
PPP1R3C
Protein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown.
    
 
 0.586
CHN2
Chimaerin; GTPase-activating protein for p21-rac.
    
 
 0.571
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.