PRKAR1A protein (Ovis aries) - STRING interaction network

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Predicted Interactions

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Score

PRKAR1A

Uncharacterized protein. (411 aa)

Predicted Functional Partners:

PRKACA

0.999

PRKACB

0.991

AKAP10

0.980

PRKAR2B

0.941

PRKAR2A

0.941

PRKX

0.912

THAP6

0.688

MIGA2

0.627

PPP2CB

0.603

AKAP11

0.583

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKAP10	AKAP11	ENSOARP00000018892	ENSOARP00000007896	A-kinase anchoring protein 10.	A-kinase anchoring protein 11.	0.612
AKAP10	PRKACA	ENSOARP00000018892	ENSOARP00000006933	A-kinase anchoring protein 10.	cAMP-dependent protein kinase catalytic subunit alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose- mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in the [...]	0.652
AKAP10	PRKACB	ENSOARP00000018892	ENSOARP00000014812	A-kinase anchoring protein 10.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.688
AKAP10	PRKAR1A	ENSOARP00000018892	ENSOARP00000016120	A-kinase anchoring protein 10.	Uncharacterized protein.	0.980
AKAP10	PRKAR2A	ENSOARP00000018892	ENSOARP00000017324	A-kinase anchoring protein 10.	Protein kinase cAMP-dependent type II regulatory subunit alpha.	0.807
AKAP10	PRKAR2B	ENSOARP00000018892	ENSOARP00000005311	A-kinase anchoring protein 10.	Protein kinase cAMP-dependent type II regulatory subunit beta.	0.807
AKAP10	PRKX	ENSOARP00000018892	ENSOARP00000009547	A-kinase anchoring protein 10.	Uncharacterized protein.	0.552
AKAP10	THAP6	ENSOARP00000018892	ENSOARP00000016444	A-kinase anchoring protein 10.	THAP domain containing 6.	0.523
AKAP11	AKAP10	ENSOARP00000007896	ENSOARP00000018892	A-kinase anchoring protein 11.	A-kinase anchoring protein 10.	0.612
AKAP11	PRKACA	ENSOARP00000007896	ENSOARP00000006933	A-kinase anchoring protein 11.	cAMP-dependent protein kinase catalytic subunit alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose- mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in the [...]	0.463
AKAP11	PRKACB	ENSOARP00000007896	ENSOARP00000014812	A-kinase anchoring protein 11.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.445
AKAP11	PRKAR1A	ENSOARP00000007896	ENSOARP00000016120	A-kinase anchoring protein 11.	Uncharacterized protein.	0.583
MIGA2	PRKAR1A	ENSOARP00000009503	ENSOARP00000016120	Mitoguardin 2.	Uncharacterized protein.	0.627
PPP2CB	PRKAR1A	ENSOARP00000000078	ENSOARP00000016120	Serine/threonine-protein phosphatase.	Uncharacterized protein.	0.603
PRKACA	AKAP10	ENSOARP00000006933	ENSOARP00000018892	cAMP-dependent protein kinase catalytic subunit alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose- mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in the [...]	A-kinase anchoring protein 10.	0.652
PRKACA	AKAP11	ENSOARP00000006933	ENSOARP00000007896	cAMP-dependent protein kinase catalytic subunit alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose- mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in the [...]	A-kinase anchoring protein 11.	0.463
PRKACA	PRKACB	ENSOARP00000006933	ENSOARP00000014812	cAMP-dependent protein kinase catalytic subunit alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose- mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in the [...]	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.900
PRKACA	PRKAR1A	ENSOARP00000006933	ENSOARP00000016120	cAMP-dependent protein kinase catalytic subunit alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose- mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in the [...]	Uncharacterized protein.	0.999
PRKACA	PRKAR2A	ENSOARP00000006933	ENSOARP00000017324	cAMP-dependent protein kinase catalytic subunit alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose- mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in the [...]	Protein kinase cAMP-dependent type II regulatory subunit alpha.	0.984
PRKACA	PRKAR2B	ENSOARP00000006933	ENSOARP00000005311	cAMP-dependent protein kinase catalytic subunit alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose- mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in the [...]	Protein kinase cAMP-dependent type II regulatory subunit beta.	0.991