STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLCN7Chloride channel protein. (759 aa)    
Predicted Functional Partners:
OSTM1
Osteoclastogenesis associated transmembrane protein 1.
   
 0.998
CLNS1A
Uncharacterized protein.
      
 0.855
ZNF280B
Zinc finger protein 280B.
      
 0.727
TCIRG1
V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
   
 
 0.706
KCNMB1
Potassium calcium-activated channel subfamily M regulatory beta subunit 1.
      
 0.699
C19orf54
Chromosome 19 open reading frame 54.
      
 0.690
W5NW12_SHEEP
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
   
  
 0.652
KCNAB2
Potassium voltage-gated channel subfamily A regulatory beta subunit 2.
      
 0.642
PRODH2
Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate.
   
  
 0.630
BSND
Barttin CLCNK type accessory beta subunit.
   
 
 0.596
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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