STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101111965PKS_ER domain-containing protein. (378 aa)    
Predicted Functional Partners:
ALDH1A1
Retinal dehydrogenase 1; Can convert/oxidize retinaldehyde to retinoic acid. Binds free retinal and cellular retinol-binding protein-bound retinal (By similarity). May have a broader specificity and oxidize other aldehydes in vivo.
 
 0.949
ALDH2
Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.
  
 0.942
ALDH7A1
Aldehyde dehydrogenase 7 family member A1; Belongs to the aldehyde dehydrogenase family.
  
 0.939
ESD
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
 0.936
ALDH3A2
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.933
ALDH1A3
Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family.
 
 0.932
ALDH9A1
Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.
  
 0.932
ALDH1A2
Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family.
 
 0.932
CYP2E1
Uncharacterized protein; Belongs to the cytochrome P450 family.
  
 
 0.927
MAOB
Amine oxidase.
   
 
 0.917
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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