STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDIA6Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family. (440 aa)    
Predicted Functional Partners:
HSP90B1
Heat shock protein 90 beta family member 1.
   
 0.974
P4HB
Protein disulfide-isomerase.
  
0.965
HSPA5
Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.
   
 0.963
ERO1A
Endoplasmic reticulum oxidoreductase 1 alpha.
   
 0.959
CALR
Calreticulin.
   
 0.958
ERO1B
Endoplasmic reticulum oxidoreductase 1 beta.
   
 0.954
ERP29
Uncharacterized protein.
   
 0.949
PDIA4
Protein disulfide-isomerase.
   
0.917
DNAJB11
J domain-containing protein.
   
 
 0.914
PRDX4
Peroxiredoxin 4.
  
 0.904
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.